Expression, purification and crystallization ofStreptococcus dysgalactiae-derived mitogen
نویسندگان
چکیده
منابع مشابه
Structural studies of superantigens: Crystal structure of Streptococcus dysgalactiae-derived mitogen (SDM)
Superantigens are a family of bacterial and viral toxins that are able to induce a massive T-cell activation [1,2]. Compared to conventional antigens where only 0.0001-0.01% of T-cells are activated, superantigens are able to activate 10-30% of T-cells. Superantigen-induced T-cell activation results in an extensive production of inflammatory cytokines, such as tumor necrosis factor and interleu...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section F Structural Biology and Crystallization Communications
سال: 2006
ISSN: 1744-3091
DOI: 10.1107/s1744309106003678